
Detroit Lions Vs Los Angeles Chargers – July 31, 2025, Betting, Prediction & Best Bets
The NFL preseason is always an exciting time for football fans and bettors alike, offering a first glimpse at revamped rosters, emerging stars, and new coaching strategies. On Thursday, July 31, 2025, the Los Angeles Chargers will travel to Ford Field to take on the Detroit Lions in a highly anticipated preseason matchup.
While preseason games don’t count toward the regular-season standings, they provide crucial insights for bettors looking to capitalize on early odds. This betting report will break down key factors, including team trends, player rotations, coaching strategies, and betting lines, to help you make informed wagers.
Game Overview
- Matchup: Los Angeles Chargers at Detroit Lions
- Date: July 31, 2025
- Time: 7:00 PM ET
- Venue: Tom Benson Hall of Fame Stadium, Canton, OH
- Broadcast: NFL Network, Local Affiliates
- Tickets: as low as $104
Betting Odds (as of Opening Lines)
- Spread: Lions -2.5 (-110) | Chargers +2.5 (-110)
- Moneyline: Lions -140 | Chargers +120
- Total (Over/Under): 37.5 points
Team Breakdowns & Betting Trends
Los Angeles Chargers: What to Watch
The Chargers enter the 2025 preseason with several key storylines:
- Quarterback Situation:
- Justin Herbert is firmly entrenched as the starter but may only play a series or two.
- Backup battle between Easton Stick and a potential rookie/UDFA could determine who gets more reps.
- If Herbert sits entirely, the Chargers’ offensive efficiency could drop significantly.
- New Coaching Influence:
- With a new offensive coordinator (if changes occurred in the offseason), play-calling tendencies may be experimental.
- Defensive schemes under new DC (if applicable) could be vanilla or aggressive in preseason testing.
- Player Rotations & Bubble Watch:
- Depth players at WR, RB, and secondary will get extended looks.
- Rookies fighting for roster spots may elevate performance.
Preseason Betting Trend:
- The Chargers are 4-6 ATS in their last 10 preseason games.
- Under has hit in 7 of their last 10 preseason contests.

Detroit Lions: Key Factors
The Lions are coming off a strong 2024 season and will use this game to evaluate depth.
- Jared Goff’s Limited Role:
- Goff may only play one or two drives, leaving backups (Hendon Hooker or a new signing) to handle most of the game.
- If Hooker plays extensively, his mobility could impact the spread.
- Dan Campbell’s Aggressiveness:
- Campbell has shown a willingness to go for it on 4th down even in preseason, which could lead to higher-scoring drives.
- Defensive rotations may be more aggressive than usual, leading to turnovers.
- Rookie & Depth Evaluations:
- The Lions’ 2025 draft class (especially late-round picks) will get significant snaps.
- Battle for WR3/4 spots could lead to explosive plays.
Preseason Betting Trend:
- Lions are 5-5 ATS in last 10 preseason games.
- Over has hit in 6 of last 10 preseason matchups.
Key Betting Angles
1. First-Half Betting (Most Predictive for Preseason)
- Since starters play early, the first-half spread/total can be a smarter play than full-game lines.
- Lions 1H Spread: -1.5 (-115)
- Chargers 1H Spread: +1.5 (-105)
- 1H Total: 18.5 points
Lean: If Herbert plays a series, Chargers 1H +1.5 could hold value.
2. Quarterback Rotations & Over/Under
- If both teams sit starters early, the game becomes a battle of backups, favoring UNDER.
- If Campbell pushes tempo, OVER 37.5 could be in play.
Recent Trends:
- Last 3 Chargers-Lions preseason meetings averaged 33.6 PPG.
3. Prop Bets to Watch
- Longest TD Over/Under 38.5 yards – Backup QBs often take deep shots.
- First TD Scorer (RBs/WRs fighting for roster spots) – Look for Lions’ 3rd-string RB or Chargers’ backup WR.
Final Prediction & Best Bets
Recommended Bets:
- Under 37.5 (-110) – Both teams likely limit starters, and backups struggle with efficiency.
- Chargers +2.5 (-110) – If Herbert plays even briefly, L.A.’s offense could outscore Detroit’s depth.
- Lions 1H ML (-120) – Early reps with Goff could give Detroit a quick lead.
Final Score Projection:
Lions 20 – Chargers 17 (Total: 37, Cover: Chargers +2.5)
Preseason NFL betting requires a focus on coaching tendencies, QB rotations, and depth charts rather than pure talent. The Chargers vs. Lions matchup offers intriguing betting opportunities, particularly in first-half markets and totals.
Monitor inactives and coaching comments leading up to kickoff for last-minute adjustments. Whether you lean Under, Chargers +2.5, or live-bet after starters exit, this game provides a solid betting foundation for the 2025 NFL preseason.
Stay disciplined, track rotations, and capitalize on early value!
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