| Buffalo Bills Schedule 2022 |
|---|
| Date | Opponent | Time/TV | Tickets |
|---|---|---|---|
| Thursday Sep. 8 | at Los Angeles Rams SoFi Stadium, Inglewood, CA | 8:20 pm ET NBC | W 31-10 |
| Monday Sep. 19 | Tennessee Titans Highmark Stadium, Orchard Park, NY | 7:15 pm ET ESPN | W 41-7 |
| Sunday Sep. 25 | at Miami Dolphins Hard Rock Stadium, Miami Gardens, FL | 1:00pm ET CBS | L 21-19 |
| Sunday Oct. 2 | at Baltimore Ravens M&T Bank Stadium, Baltimore, MD | 1:00pm ET CBS | W 23-20 |
| Sunday Oct. 9 | Pittsburgh Steelers Highmark Stadium, Orchard Park, NY | 1:00pm ET CBS | W 38-3 |
| Sunday Oct. 16 | at Kansas City Chiefs Arrowhead Stadium, Kansas City, MO | 4:25 pm ET CBS | W 24-20 |
| Sunday Oct. 23 | BYE++ | ||
| Sunday Oct. 30 | Green Bay Packers Highmark Stadium, Orchard Park, NY | 8:20 pm ET NBC | Buy Tickets |
| Sunday Nov. 6 | at New York Jets MetLife Stadium, East Rutherford, NJ | 1:00pm ET CBS | Buy Tickets |
| Sunday Nov. 13 | Minnesota Vikings Highmark Stadium, Orchard Park, NY | 1:00 pm ET FOX | Buy Tickets |
| Sunday Nov. 20 | Cleveland Browns Highmark Stadium, Orchard Park, NY | 1:00pm ET CBS | Buy Tickets |
| Thursday Nov. 24 | at Detroit Lions Ford Field, Detroit, MI | 12:30 pm ET CBS | Buy Tickets |
| Thursday Dec. 1 | at New England Patriots Gillette Stadium, Foxborough, MA | 8:15 pm ET Prime Video | Buy Tickets |
| Sunday Dec. 11 | New York Jets Highmark Stadium, Orchard Park, NY | 1:00pm ET CBS | Buy Tickets |
| Saturday Dec. 17 | Miami Dolphins Highmark Stadium, Orchard Park, NY | Time TBA ET or Sun., Dec. 18 | Buy Tickets |
| Saturday Dec. 24 | at Chicago Bears Soldier Field, Chicago, IL | 1:00pm ET CBS | Buy Tickets |
| Monday Jan. 2 | at Cincinnati Bengals Paycor Stadium, Cincinnati, OH | 8:30 pm ET ESPN/ABC | Buy Tickets |
| Sunday Jan. 8 | New England Patriots Highmark Stadium, Orchard Park, NY | Time TBA ET or Sat., Jan. 7 | Buy Tickets |
