Thursday, November 17, 2022
| AWAY | HOME | RESULT |
| Tennessee | Green Bay | TEN 27 – GB 17 |
Sunday, November 20, 2022
| AWAY | HOME | RESULT |
| Chicago | Atlanta | ATL 27 – CHI 24 |
| Carolina | Baltimore | BAL 13 – CAR 3 |
| Cleveland | Buffalo | BUF 31 – CLE 23 |
| Detroit | N.Y. Giants | DET 31 – NYG 18 |
| L.A. Rams | New Orleans | NO 27 – LAR 20 |
| N.Y. Jets | New England | NE 10 – NYJ 3 |
| Philadelphia | Indianapolis | PHI 17 – IND 16 |
| Washington | Houston | WAS 23 – HOU 10 |
| Las Vegas | Denver | LV 22 – DEN 16 / OT |
| Cincinnati | Pittsburgh | CIN 37 – PIT 30 |
| Dallas | Minnesota | DAL 40 – MIN 3 |
| Kansas City | L.A. Chargers | KC 30 – LAC 27 |
Monday, November 21, 2022
| AWAY | HOME | RESULT |
| San Francisco | Arizona | SF 38 – ARI 10 |
