| Thursday, October 9, 2025 | Tampa Bay Buccaneers at Atlanta Falcons | 8:15 PM | AMZN | FuboTV | Mercedes-Benz Stadium | Buy Tickets |
| Sunday, October 12, 2025 | Cincinnati Bengals at Baltimore Ravens | 1:00 PM | CBS | FuboTV | M&T Bank Stadium | Buy Tickets |
| Sunday, October 12, 2025 | Cleveland Browns at Pittsburgh Steelers | 1:00 PM | CBS | FuboTV | Acrisure Stadium | Buy Tickets |
| Sunday, October 12, 2025 | Detroit Lions at Green Bay Packers | 1:00 PM | FOX | FuboTV | Lambeau Field | Buy Tickets |
| Sunday, October 12, 2025 | Houston Texans at Jacksonville Jaguars | 1:00 PM | CBS | FuboTV | EverBank Stadium | Buy Tickets |
| Sunday, October 12, 2025 | New England Patriots at Miami Dolphins | 1:00 PM | CBS | FuboTV | Hard Rock Stadium | Buy Tickets |
| Sunday, October 12, 2025 | New Orleans Saints at Carolina Panthers | 1:00 PM | FOX | FuboTV | Bank of America Stadium | Buy Tickets |
| Sunday, October 12, 2025 | San Francisco 49ers at Seattle Seahawks | 4:05 PM | FOX | FuboTV | Lumen Field | Buy Tickets |
| Sunday, October 12, 2025 | Dallas Cowboys at New York Giants | 4:25 PM | CBS | FuboTV | MetLife Stadium | Buy Tickets |
| Sunday, October 12, 2025 | Kansas City Chiefs at Denver Broncos | 8:20 PM | NBC | FuboTV | Empower Field at Mile High | Buy Tickets |
| Monday, October 13, 2025 | Arizona Cardinals at Chicago Bears | 8:15 PM | ESPN | FuboTV | Soldier Field | Buy Tickets |